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A robust crystal packing interface between protein monomers obscures the true DNA-binding surface, known from previous genetic and biochemical studies. By ...
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Jun 5, 2021 · This work presents a powerful new approach to redefining the interactions between proteins within single crystals using programmable DNA ligands ...
Jul 27, 2021 · Protein–DNA complexes represent the molecular interface between stimulus and response for all organisms, and three-dimensional structures of ...
May 18, 2010 · The database includes a simple functional classification of the protein-DNA complexes that consists of three hierarchical levels: Class, Type ...
Feb 13, 2020 · Complexes between proteins are at the basis of almost every process in cells. Their study, from a structural perspective, has a pivotal role ...
Analysis of this crystal structure provides important insight into the molecular mechanisms underlying the protection of both the protein and DNA components of ...
In this work, we present a method that contributes to decipher such complexity by predicting protein-DNA interfaces and characterizing their properties. It ...
For proteins that bind nucleic acid without sequence specificity, crystallization of protein-nucleic acid complex is not hopeless. Crystal lattice packing may ...
Missing: Interface|
The DNA fragments in the crystal are packed end-to-end to form a pseudocontinuous helix. If contacts to these neighbors are taken into account (Figure 2D), the ...
Abstract. To investigate the principles driving recognition between proteins and DNA, we analyzed more than thousand crystal structures of protein/DNA comp.